ARP3B_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ACTR3B , ARP11, ARP4
Protein names and data: ARP3B_HUMAN , Actin-related protein 3B , ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4 Lenght: 418 a.a.
Mass: 47608 Da
fasta formatted sequence
Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Cellular location: Cytoplasm, cytoskeleton (By similarity). Cell projection (By similarity).
Tissue specificity: Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential.

Genetic variants

Database cross-references

UniProt: Q9P1U1
Ensembl: ENST00000256001
Ensembl: ENST00000377776
Ensembl: ENST00000397282
Ensembl: ENST00000537264
neXtProt: NX_Q9P1U1
Antibodypedia: Q9P1U1 (may not find the protein thus also not any antibody)
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