RBCC Red Blood Cell Collection

CATA_HUMAN

Source: hRBCD ; ID: IPI00465436
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: CAT
Protein names and data: CATA_HUMAN , Catalase; 1.11.1.6 Lenght: 527 a.a.
Mass: 59756 Da
fasta formatted sequence
Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Catalytic activity: 2 H(2)O(2) = O(2) + 2 H(2)O.
Disease: ( OMIM: 115500 614097 ) Acatalasemia (ACATLAS) [MIM:614097]: A metabolic disorder characterized by a total or near total loss of catalase activity in red cells. It is often associated with ulcerating oral lesions. Note=The disease is caused by mutations affecting the gene represented in this entry.
Cellular location: Peroxisome.

Database cross-references

UniProt: P04040
Ensembl: ENST00000241052
MIM: 115500
MIM: 614097
neXtProt: NX_P04040
Antibodypedia: P04040 (may not find the protein thus also not any antibody)
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