CPIN1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CIAPIN1 , CUA001, PRO0915
Protein names and data: CPIN1_HUMAN , Anamorsin , Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog Lenght: 312 a.a.
Mass: 33582 Da
fasta formatted sequence
Function: Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1.
Cellular location: Cytoplasm. Nucleus. Mitochondrion. Mitochondrion intermembrane space (Probable). Note=Imported into mitochondria (in vitro).
Tissue specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Genetic variants

Database cross-references

UniProt: Q6FI81
Ensembl: ENST00000394391
Ensembl: ENST00000567518
MIM: 608943
neXtProt: NX_Q6FI81
Antibodypedia: Q6FI81 (may not find the protein thus also not any antibody)
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