DGKD_HUMAN

Source: hRBCD ; ID: IPI00374804
PM23856902
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: DGKD , KIAA0145
Protein names and data: DGKD_HUMAN , Diacylglycerol kinase delta; DAG kinase delta; 2.7.1.107 , 130 kDa diacylglycerol kinase; Diglyceride kinase delta; DGK-delta Lenght: 1214 a.a.
Mass: 134525 Da
fasta formatted sequence
Function: May function as signaling molecule. Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.
Catalytic activity: ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl- sn-glycerol 3-phosphate.
Cellular location: Isoform 2: Cytoplasm. Isoform 1: Membrane; Peripheral membrane protein.
Tissue specificity: Isoform 2 is ubiquitously expressed also in tumor tissues. Isoform 1 is expressed in ovary, spleen and some tumor-derived cells.

Database cross-references

UniProt: Q16760
Ensembl: ENST00000264057
Ensembl: ENST00000409813
MIM: 601826
neXtProt: NX_Q16760
Antibodypedia: Q16760 (may not find the protein thus also not any antibody)
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