DPYL2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: DPYSL2 , CRMP2, ULIP2
Protein names and data: DPYL2_HUMAN , Dihydropyrimidinase-related protein 2; DRP-2 , Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2 Lenght: 572 a.a.
Mass: 62294 Da
fasta formatted sequence

Function: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Cellular location: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Note=Tightly but non-covalently associated with membranes.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: Q16555
Ensembl: ENST00000311151
Ensembl: ENST00000521913
Ensembl: ENST00000523027
MIM: 602463
neXtProt: NX_Q16555
Antibodypedia: Q16555 (may not find the protein thus also not any antibody)
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