Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: HIST2H2AB
Protein names and data: H2A2B_HUMAN , Histone H2A type 2-B Lenght: 130 a.a.
Mass: 13995 Da
fasta formatted sequence

Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular location: Nucleus. Chromosome.

Genetic variants

Database cross-references

UniProt: Q8IUE6
Ensembl: ENST00000331128
Ensembl: ENST00000579360
MIM: 615014
neXtProt: NX_Q8IUE6
Antibodypedia: Q8IUE6 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.