HRH4_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: HRH4 , GPCR105
Protein names and data: HRH4_HUMAN , Histamine H4 receptor; H4R; HH4R , AXOR35; G-protein coupled receptor 105; GPRv53; Pfi-013; SP9144 Lenght: 390 a.a.
Mass: 44496 Da
fasta formatted sequence
Function: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node.

Genetic variants

Database cross-references

UniProt: Q9H3N8
Ensembl: ENST00000256906
Ensembl: ENST00000426880
MIM: 606792
neXtProt: NX_Q9H3N8
Antibodypedia: Q9H3N8 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.