LANC2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: LANCL2 , GPR69B, TASP
Protein names and data: LANC2_HUMAN , LanC-like protein 2 , Testis-specific adriamycin sensitivity protein Lenght: 450 a.a.
Mass: 50854 Da
fasta formatted sequence
Function: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.
Cellular location: Nucleus. Cytoplasm. Cell membrane. Note=Localizes to the juxta-nuclear vesicles. Associates with the cortical actin cytoskeleton. Cholesterol depletion by methyl-beta- cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo. Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin).
Tissue specificity: Expressed in brain and testis.

Genetic variants

Database cross-references

UniProt: Q9NS86
Ensembl: ENST00000254770
MIM: 612919
neXtProt: NX_Q9NS86
Antibodypedia: Q9NS86 (may not find the protein thus also not any antibody)
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