LAT3_HUMAN

Source: hRBCD ; ID: IPI00021075
PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: SLC43A1 , LAT3, PB39, POV1
Protein names and data: LAT3_HUMAN , Large neutral amino acids transporter small subunit 3 , L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1 Lenght: 559 a.a.
Mass: 61477 Da
fasta formatted sequence
Function: Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
Cellular location: Membrane; Multi-pass membrane protein (Probable).
Tissue specificity: In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.

Genetic variants

Database cross-references

UniProt: O75387
Ensembl: ENST00000278426
Ensembl: ENST00000528450
MIM: 603733
neXtProt: NX_O75387
Antibodypedia: O75387 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.