PDE6D_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: PDE6D , PDED
Protein names and data: PDE6D_HUMAN , Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; GMP-PDE delta , Protein p17 Lenght: 150 a.a.
Mass: 17420 Da
fasta formatted sequence

Function: Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation (By similarity).
Cellular location: Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Peripheral membrane protein.
Tissue specificity: Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.

Database cross-references

UniProt: O43924
Ensembl: ENST00000287600
MIM: 602676
neXtProt: NX_O43924
Antibodypedia: O43924 (may not find the protein thus also not any antibody)
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