TIAF1_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: TIAF1
Protein names and data: TIAF1_HUMAN , TGFB1-induced anti-apoptotic factor 1 , 12 kDa TGF-beta-1-induced antiapoptotic factor Lenght: 115 a.a.
Mass: 12414 Da
fasta formatted sequence

Function: Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
Cellular location: Nucleus.
Tissue specificity: Not detectable in normal kidney and liver. Up- regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.

Database cross-references

UniProt: O95411
Ensembl: ENST00000359450
Ensembl: ENST00000408971
MIM: 609517
neXtProt: NX_O95411
Antibodypedia: O95411 (may not find the protein thus also not any antibody)
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