WIPI2_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: WIPI2 , CGI-50
Protein names and data: WIPI2_HUMAN , WD repeat domain phosphoinositide-interacting protein 2; WIPI-2 , WIPI49-like protein 2 Lenght: 454 a.a.
Mass: 49408 Da
fasta formatted sequence
Function: Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P.
Cellular location: Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side. Note=Enriched at preautophagosomal structure membranes in response to ptdIns3P.
Tissue specificity: Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors.

Database cross-references

UniProt: Q9Y4P8
Ensembl: ENST00000288828
Ensembl: ENST00000382384
Ensembl: ENST00000401525
Ensembl: ENST00000404704
Ensembl: ENST00000484262
MIM: 609225
neXtProt: NX_Q9Y4P8
Antibodypedia: Q9Y4P8 (may not find the protein thus also not any antibody)
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